Assessment of genetically modified soybean GMB151 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2018‐153)
Abstract Soybean GMB151 was developed to confer tolerance to 4‐hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor herbicides and resistance to nematodes. The molecular characterisation data and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the identifie...
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| Format: | Article |
| Language: | English |
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Wiley
2021-04-01
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| Series: | EFSA Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.2903/j.efsa.2021.6424 |
| _version_ | 1819127843432431616 |
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| author | EFSA Panel on Genetically Modified Organisms (GMO) Hanspeter Naegeli Jean Louis Bresson Tamas Dalmay Ian Crawford Dewhurst Michelle M Epstein Leslie George Firbank Philippe Guerche Jan Hejatko Francisco Javier Moreno Ewen Mullins Fabien Nogué Nils Rostoks Jose Juan Sánchez Serrano Giovanni Savoini Eve Veromann Fabio Veronesi Fernando Álvarez Michele Ardizzone Silvia Federici Antonio Fernandez Andrea Gennaro Jose Ángel Gómez Ruiz Dafni Maria Kagkli Anna Lanzoni Franco Maria Neri Nikoletta Papadopoulou Konstantinos Paraskevopoulos Tommaso Raffaello Franz Streissl Giacomo De Sanctis |
| author_facet | EFSA Panel on Genetically Modified Organisms (GMO) Hanspeter Naegeli Jean Louis Bresson Tamas Dalmay Ian Crawford Dewhurst Michelle M Epstein Leslie George Firbank Philippe Guerche Jan Hejatko Francisco Javier Moreno Ewen Mullins Fabien Nogué Nils Rostoks Jose Juan Sánchez Serrano Giovanni Savoini Eve Veromann Fabio Veronesi Fernando Álvarez Michele Ardizzone Silvia Federici Antonio Fernandez Andrea Gennaro Jose Ángel Gómez Ruiz Dafni Maria Kagkli Anna Lanzoni Franco Maria Neri Nikoletta Papadopoulou Konstantinos Paraskevopoulos Tommaso Raffaello Franz Streissl Giacomo De Sanctis |
| author_sort | EFSA Panel on Genetically Modified Organisms (GMO) |
| collection | DOAJ |
| description | Abstract Soybean GMB151 was developed to confer tolerance to 4‐hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor herbicides and resistance to nematodes. The molecular characterisation data and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the identified differences in the agronomic/phenotypic and compositional characteristics tested between soybean GMB151 and its conventional counterpart needs further assessment, except for palmitic acid and heptadecenoic acid in seeds and carbohydrate and crude protein in forage, which does not raise nutritional and safety concerns. The GMO Panel does not identify safety concerns regarding the toxicity and allergenicity of the HPPD‐4 and Cry14Ab‐1 proteins as expressed in soybean GMB151, and finds no evidence that the genetic modification would change the overall allergenicity of soybean GMB151. In the context of this application, the consumption of food and feed from soybean GMB151 does not represent a nutritional concern in humans and animals. The GMO Panel concludes that soybean GMB151 is as safe as the conventional counterpart and non‐GM soybean reference varieties tested, and no post‐market monitoring of food/feed is considered necessary. In the case of accidental release of viable soybean GMB151 seeds into the environment, this would not raise environmental safety concerns. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of soybean GMB151. The GMO Panel concludes that soybean GMB151 is as safe as its conventional counterpart and the tested non‐GM soybean reference varieties with respect to potential effects on human and animal health and the environment. |
| first_indexed | 2024-12-22T08:18:22Z |
| format | Article |
| id | doaj.art-3cc2473b519240b7b40924aaa9e12376 |
| institution | Directory Open Access Journal |
| issn | 1831-4732 |
| language | English |
| last_indexed | 2024-12-22T08:18:22Z |
| publishDate | 2021-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj.art-3cc2473b519240b7b40924aaa9e123762022-12-21T18:32:49ZengWileyEFSA Journal1831-47322021-04-01194n/an/a10.2903/j.efsa.2021.6424Assessment of genetically modified soybean GMB151 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2018‐153)EFSA Panel on Genetically Modified Organisms (GMO)Hanspeter NaegeliJean Louis BressonTamas DalmayIan Crawford DewhurstMichelle M EpsteinLeslie George FirbankPhilippe GuercheJan HejatkoFrancisco Javier MorenoEwen MullinsFabien NoguéNils RostoksJose Juan Sánchez SerranoGiovanni SavoiniEve VeromannFabio VeronesiFernando ÁlvarezMichele ArdizzoneSilvia FedericiAntonio FernandezAndrea GennaroJose Ángel Gómez RuizDafni Maria KagkliAnna LanzoniFranco Maria NeriNikoletta PapadopoulouKonstantinos ParaskevopoulosTommaso RaffaelloFranz StreisslGiacomo De SanctisAbstract Soybean GMB151 was developed to confer tolerance to 4‐hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor herbicides and resistance to nematodes. The molecular characterisation data and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the identified differences in the agronomic/phenotypic and compositional characteristics tested between soybean GMB151 and its conventional counterpart needs further assessment, except for palmitic acid and heptadecenoic acid in seeds and carbohydrate and crude protein in forage, which does not raise nutritional and safety concerns. The GMO Panel does not identify safety concerns regarding the toxicity and allergenicity of the HPPD‐4 and Cry14Ab‐1 proteins as expressed in soybean GMB151, and finds no evidence that the genetic modification would change the overall allergenicity of soybean GMB151. In the context of this application, the consumption of food and feed from soybean GMB151 does not represent a nutritional concern in humans and animals. The GMO Panel concludes that soybean GMB151 is as safe as the conventional counterpart and non‐GM soybean reference varieties tested, and no post‐market monitoring of food/feed is considered necessary. In the case of accidental release of viable soybean GMB151 seeds into the environment, this would not raise environmental safety concerns. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of soybean GMB151. The GMO Panel concludes that soybean GMB151 is as safe as its conventional counterpart and the tested non‐GM soybean reference varieties with respect to potential effects on human and animal health and the environment.https://doi.org/10.2903/j.efsa.2021.6424GMOsoybean (Glycine max)GMB151Regulation (EC) 1829/2003HPPD‐4Cry14Ab‐1 |
| spellingShingle | EFSA Panel on Genetically Modified Organisms (GMO) Hanspeter Naegeli Jean Louis Bresson Tamas Dalmay Ian Crawford Dewhurst Michelle M Epstein Leslie George Firbank Philippe Guerche Jan Hejatko Francisco Javier Moreno Ewen Mullins Fabien Nogué Nils Rostoks Jose Juan Sánchez Serrano Giovanni Savoini Eve Veromann Fabio Veronesi Fernando Álvarez Michele Ardizzone Silvia Federici Antonio Fernandez Andrea Gennaro Jose Ángel Gómez Ruiz Dafni Maria Kagkli Anna Lanzoni Franco Maria Neri Nikoletta Papadopoulou Konstantinos Paraskevopoulos Tommaso Raffaello Franz Streissl Giacomo De Sanctis Assessment of genetically modified soybean GMB151 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2018‐153) EFSA Journal GMO soybean (Glycine max) GMB151 Regulation (EC) 1829/2003 HPPD‐4 Cry14Ab‐1 |
| title | Assessment of genetically modified soybean GMB151 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2018‐153) |
| title_full | Assessment of genetically modified soybean GMB151 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2018‐153) |
| title_fullStr | Assessment of genetically modified soybean GMB151 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2018‐153) |
| title_full_unstemmed | Assessment of genetically modified soybean GMB151 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2018‐153) |
| title_short | Assessment of genetically modified soybean GMB151 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2018‐153) |
| title_sort | assessment of genetically modified soybean gmb151 for food and feed uses under regulation ec no 1829 2003 application efsa gmo nl 2018 153 |
| topic | GMO soybean (Glycine max) GMB151 Regulation (EC) 1829/2003 HPPD‐4 Cry14Ab‐1 |
| url | https://doi.org/10.2903/j.efsa.2021.6424 |
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