Vaccine Against PCSK9 Improved Renal Fibrosis by Regulating Fatty Acid β‐Oxidation

Vaccine Against PCSK9 Improved Renal Fibrosis by Regulating Fatty Acid β‐Oxidation

Background Defects in the renal fatty acid β‐oxidation pathway have been implicated in the development of renal fibrosis. Our group has developed a therapeutic vaccine targeting PCSK9 (proprotein convertase subtilisin/kexin type 9), named PCSK9Qβ‐003. In this study, we investigated the potential eff...

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Bibliographic Details
Main Authors: Danyu Wu, Yanzhao Zhou, Yajie Pan, Chang Li, Yingxuan Wang, Fen Chen, Xiao Chen, Shijun Yang, Zihua Zhou, Yuhua Liao, Zhihua Qiu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
fatty acid β‐oxidation
hyperlipidemia
proprotein convertase subtilisin/kexin type 9
renal fibrosis
vaccine
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.014358

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https://www.ahajournals.org/doi/10.1161/JAHA.119.014358

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