Indoleamine 2,3‐dioxygenase gene expression and kynurenine to tryptophan ratio correlation with nasopharyngeal carcinoma progression and survival

Abstract Introduction Indoleamine 2,3‐dioxygenase (IDO) is an immunosuppressive tryptophan‐depleting enzyme expressed in nasopharyngeal carcinoma (NPC) tissue. However, IDO has not been reported in the peripheral blood of NPC patients. The aim of this study was to analyze, IDO1 and IDO2 messenger RN...

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Main Authors: Sameh Souissi, Randa Ghedira, Yosra Macherki, Ahlem Ben‐Haj‐Ayed, Sallouha Gabbouj, Yasmine Remadi, Imen Sfar, Zohra Chadli, Karim Aouam, Mohsen Hassine, Noureddine Bouaouina, Abdelfattah Zakhama, Elham Hassen
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Immunity, Inflammation and Disease
Subjects:
Online Access:https://doi.org/10.1002/iid3.690