Unique trophoblast chromatin environment mediated by the PcG protein SFMBT2

Stem/progenitor cells are maintained by a chromatin environment, mediated in part by Polycomb group (PcG) proteins, which depress differentiation. The trophoblast-specific PcG protein SFMBT2 is known to be required for maintenance of trophoblast progenitors. Rather than binding to trophoblast-specif...

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Bibliographic Details
Main Authors: Priscilla Tang, Kamelia Miri, Susannah Varmuza
Format: Article
Language:English
Published: The Company of Biologists 2019-08-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/8/8/bio043638