Secondary lesions and sensitivity to signaling inhibitors in iAMP21 acute lymphoblastic leukemia
Abstract Intrachromosomal amplification of chromosome 21 (iAMP21) B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL) in children is a high‐risk subtype for which targeted drugs are lacking. In this study, we determined the frequency of secondary lesions in 28 iAMP21 BCP‐ALL patient samples and...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | HemaSphere |
| Online Access: | https://doi.org/10.1002/hem3.70069 |