Autophagy and senescence facilitate the development of antiestrogen resistance in ER positive breast cancer

Autophagy and senescence facilitate the development of antiestrogen resistance in ER positive breast cancer

Estrogen receptor positive (ER+) breast cancer is the most common breast cancer diagnosed annually in the US with endocrine-based therapy as standard-of-care for this breast cancer subtype. Endocrine therapy includes treatment with antiestrogens, such as selective estrogen receptor modulators (SERMs...

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Bibliographic Details
Main Authors: Michael K. McGrath, Ali Abolhassani, Luke Guy, Ahmed M. Elshazly, John T. Barrett, Nahid F. Mivechi, David A. Gewirtz, Patricia V. Schoenlein
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Endocrinology
Subjects:
autophagy
senescence
endocrine resistance
breast cancer
SERMs
SERDs
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1298423/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2024.1298423/full

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