SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication.
Small ubiquitin-like modifier (SUMO) modification of chromatin has profound effects on transcription regulation. By using Kaposi's sarcoma associated herpesvirus (KSHV) as a model, we recently demonstrated that epigenetic modification of viral chromatin by SUMO-2/3 is involved in regulating gen...
| Hlavní autoři: | , , |
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| Médium: | Článek |
| Jazyk: | English |
| Vydáno: |
Public Library of Science (PLoS)
2017-02-01
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| Edice: | PLoS Pathogens |
| On-line přístup: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006216&type=printable |