SAA1 increases NOX4/ROS production to promote LPS-induced inflammation in vascular smooth muscle cells through activating p38MAPK/NF-κB pathway

SAA1 increases NOX4/ROS production to promote LPS-induced inflammation in vascular smooth muscle cells through activating p38MAPK/NF-κB pathway

Abstract Background To investigate the effects of serum amyloid A1 (SAA1) on lipopolysaccharide (LPS) -induced inflammation in vascular smooth muscle cells (VSMCs). SAA1 expression was detected in LPS induced VSMCs at different concentrations for different time by using Western blotting. After pre-i...

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Bibliographic Details
Main Authors: Mei-Hong Yu, Xi Li, Qian Li, Shi-Jing Mo, Yin Ni, Fang Han, Yi-Bin Wang, Yue-Xing Tu
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Molecular and Cell Biology
Subjects:
Serum amyloid A1
Vascular smooth muscle cell
LPS
Inflammation
NOX-4/ROS
p38MAPK/NF-κB
Online Access:http://link.springer.com/article/10.1186/s12860-019-0197-0

Internet

http://link.springer.com/article/10.1186/s12860-019-0197-0

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