Aedes aegypti D7 long salivary proteins modulate blood feeding and parasite infection

Aedes aegypti D7 long salivary proteins modulate blood feeding and parasite infection

ABSTRACTMosquito saliva facilitates blood meal acquisition through pharmacologically active compounds that prevent host hemostasis and immune responses. Here, we generated two knockout (KO) mosquito lines by CRISPR/Cas9 to functionally characterize D7L1 and D7L2, two abundantly expressed salivary pr...

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Bibliographic Details
Main Authors: Ines Martin-Martin, Bianca Burini Kojin, Azadeh Aryan, Adeline E. Williams, Alvaro Molina-Cruz, Paola Carolina Valenzuela-Leon, Gaurav Shrivastava, Karina Botello, Mahnaz Minai, Zach N. Adelman, Eric Calvo
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mBio
Subjects:
gene editing
arthropod
hematophagy
vascular biology
Plasmodium
Online Access:https://journals.asm.org/doi/10.1128/mbio.02289-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02289-23

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