EZH2-H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis

EZH2-H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis

Enhancer of zeste homolog 2 (EZH2) has been associated with poor prognosis in triple negative breast cancer (TNBC). Here, the authors suggest a potential role for trimethylation function of EZH2 in driving peritoneal metastasis in TNBC.

Bibliographic Details
Main Authors: Ayushi Verma, Akhilesh Singh, Manish Pratap Singh, Mushtaq Ahmad Nengroo, Krishan Kumar Saini, Saumya Ranjan Satrusal, Muqtada Ali Khan, Priyank Chaturvedi, Abhipsa Sinha, Sanjeev Meena, Anup Kumar Singh, Dipak Datta
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35059-x

Internet

https://doi.org/10.1038/s41467-022-35059-x

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