DPP-4 inhibitor attenuates toxic effects of indoxyl sulfate on kidney tubular cells.

DPP-4 inhibitor attenuates toxic effects of indoxyl sulfate on kidney tubular cells.

Diabetic nephropathy is a common causative factor of chronic kidney disease (CKD). DPP-4 inhibitor has the ability to improve kidney function and renal microvasculature. In the present study, we investigate the deleterious effects of IS on proximal tubular cells and the protective role of DPP-4 inhi...

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Bibliographic Details
Main Authors: Wei-Jie Wang, Chen-Hung Chang, Mao-Feng Sun, Sheng-Feng Hsu, Ching-Sung Weng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3995638?pdf=render

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http://europepmc.org/articles/PMC3995638?pdf=render

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