DPP-4 inhibitor attenuates toxic effects of indoxyl sulfate on kidney tubular cells.
Diabetic nephropathy is a common causative factor of chronic kidney disease (CKD). DPP-4 inhibitor has the ability to improve kidney function and renal microvasculature. In the present study, we investigate the deleterious effects of IS on proximal tubular cells and the protective role of DPP-4 inhi...
Main Authors: | Wei-Jie Wang, Chen-Hung Chang, Mao-Feng Sun, Sheng-Feng Hsu, Ching-Sung Weng |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3995638?pdf=render |
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