R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1

R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1

Maintenance of genome stability is crucial for cell survival and relies on accurate DNA replication. However, replication fork progression is under constant attack from different exogenous and endogenous factors that can give rise to replication stress, a source of genomic instability and a notable...

Full description

Bibliographic Details
Main Authors: Veronica Marabitti, Pasquale Valenzisi, Giorgia Lillo, Eva Malacaria, Valentina Palermo, Pietro Pichierri, Annapaola Franchitto
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
genomic instability
replication stress
DNA repair
RecQ helicases
R-loops
Online Access:https://www.mdpi.com/1422-0067/23/3/1547

Internet

https://www.mdpi.com/1422-0067/23/3/1547

Similar Items