Nasal high-flow compared to non-invasive ventilation in treatment of acute acidotic hypercapnic exacerbation of chronic obstructive pulmonary disease—protocol for a randomized controlled noninferiority trial (ELVIS)

Nasal high-flow compared to non-invasive ventilation in treatment of acute acidotic hypercapnic exacerbation of chronic obstructive pulmonary disease—protocol for a randomized controlled noninferiority trial (ELVIS)

Abstract Background Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have a major negative impact on health status, rates of hospitalization, readmission, disease progression and mortality. Non-invasive ventilation (NIV) is the standard therapy for hypercapnic acidotic respirato...

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Bibliographic Details
Main Authors: Jens Bräunlich, Nicole Köppe-Bauernfeind, David Petroff, Annegret Franke, Hubert Wirtz
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Trials
Subjects:
Chronic obstructive pulmonary disease
COPD
Nasal high-flow
Non-invasive ventilation
Acidotic hypercapnic exacerbation
intubation
Online Access:https://doi.org/10.1186/s13063-021-05978-z

Internet

https://doi.org/10.1186/s13063-021-05978-z

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