T Cell Immunoglobulin and Mucin Domain 3 (TIM-3) in Cutaneous Melanoma: A Narrative Review

T Cell Immunoglobulin and Mucin Domain 3 (TIM-3) in Cutaneous Melanoma: A Narrative Review

T cell immunoglobulin and mucin domain 3 (TIM-3) is an inhibitory immunocheckpoint that belongs to the TIM gene family. Monney et al. first discovered it about 20 years ago and linked it to some autoimmune diseases; subsequent studies have revealed that some tumours, including melanoma, have the cap...

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Bibliographic Details
Main Authors: Gerardo Cazzato, Eliano Cascardi, Anna Colagrande, Teresa Lettini, Alessandra Filosa, Francesca Arezzo, Carmelo Lupo, Nadia Casatta, Vera Loizzi, Cristina Pellegrini, Maria Concetta Fargnoli, Eugenio Maiorano, Gerolamo Cicco, Roberto Tamma, Giuseppe Ingravallo
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
TIM-3
T cell immunoglobulin and mucin domain 3
Immunocheckpoint inhibitors
immunotherapy
HMGB1
melanoma
Online Access:https://www.mdpi.com/2072-6694/15/6/1697

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https://www.mdpi.com/2072-6694/15/6/1697

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