Docking and Molecular Dynamics Study to Identify Novel Phytobiologics from <i>Dracaena trifasciata</i> against Metabolic Reprogramming in Rheumatoid Arthritis

Docking and Molecular Dynamics Study to Identify Novel Phytobiologics from <i>Dracaena trifasciata</i> against Metabolic Reprogramming in Rheumatoid Arthritis

Enhancement of glycolysis and glutaminolysis are the two most common modalities associated with metabolic reprogramming in rheumatoid arthritis (RA). This enhancement is concomitant to the upregulation of hexokinase 2 (HK2) and glutaminase 1 (GLS1). Hence, the current study was undertaken to identif...

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Bibliographic Details
Main Authors: Shanzay Ahmed, Peter John, Rehan Zafar Paracha, Attya Bhatti, Monica Guma
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Life
Subjects:
<i>Dracaena trifasciata</i>
GLS1
HK2
metabolic reprogramming
rheumatoid arthritis
Online Access:https://www.mdpi.com/2075-1729/12/8/1148

Internet

https://www.mdpi.com/2075-1729/12/8/1148

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