Long non-coding RNA taurine upregulated gene 1 is downregulated in osteoporosis and influences the osteogenic differentiation of bone marrow mesenchymal stem cells

Long non-coding RNA taurine upregulated gene 1 is downregulated in osteoporosis and influences the osteogenic differentiation of bone marrow mesenchymal stem cells

Background With aging, an imbalance in bone remodeling leading to increased bone resorption and decreased bone formation is thought to contribute to osteoporosis. Osteoblastic differentiation of bone marrow mesenchymal stem cells (BMMSCs) plays a vital role in the pathogenesis of osteoporosis. Howev...

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Bibliographic Details
Main Authors: Zhaowei Teng, Yun Zhu, Qinggang Hao, Xiaochao Yu, Yirong Teng, Qiaoning Yue, Xiguang Zhang, Sheng Lu
Format: Article
Language:English
Published: PeerJ Inc. 2021-04-01
Series:PeerJ
Subjects:
Osteoporosis
LncRNA TUG1
miR-23b
Osteogenic differentiation
TUG1/miR-23b/RUNX2 signaling pathway
Online Access:https://peerj.com/articles/11251.pdf

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https://peerj.com/articles/11251.pdf

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