Identification of MTHFD2 as a prognostic biomarker and ferroptosis regulator in triple-negative breast cancer

Identification of MTHFD2 as a prognostic biomarker and ferroptosis regulator in triple-negative breast cancer

BackgroundMethylenetetrahydrofolate dehydrogenase 2 (MTHFD2) is a mitochondrial bifunctional enzyme encoded in the nucleus. It plays a significant role in the regulation of glucose, nucleic acid, and folate metabolism, and maintains redox balance in the cells. The present study aimed at elucidating...

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Bibliographic Details
Main Authors: Hao Zhang, Shuangli Zhu, Haiting Zhou, Rui Li, Xiaohui Xia, Huihua Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
MTHFD2
breast cancer
bioinformatics
prognosis
biomarker
ferroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1098357/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1098357/full

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