Identification of MTHFD2 as a prognostic biomarker and ferroptosis regulator in triple-negative breast cancer

BackgroundMethylenetetrahydrofolate dehydrogenase 2 (MTHFD2) is a mitochondrial bifunctional enzyme encoded in the nucleus. It plays a significant role in the regulation of glucose, nucleic acid, and folate metabolism, and maintains redox balance in the cells. The present study aimed at elucidating...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Hao Zhang, Shuangli Zhu, Haiting Zhou, Rui Li, Xiaohui Xia, Huihua Xiong
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Frontiers Media S.A. 2023-01-01
Σειρά:Frontiers in Oncology
Θέματα:
Διαθέσιμο Online:https://www.frontiersin.org/articles/10.3389/fonc.2023.1098357/full