Comprehensive benchmark and architectural analysis of deep learning models for nanopore sequencing basecalling

Abstract Background Nanopore-based DNA sequencing relies on basecalling the electric current signal. Basecalling requires neural networks to achieve competitive accuracies. To improve sequencing accuracy further, new models are continuously proposed with new architectures. However, benchmarking is c...

Full description

Bibliographic Details
Main Authors: Marc Pagès-Gallego, Jeroen de Ridder
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-023-02903-2