Parkinson’s disease in a patient with GBA and LRRK2 covariants after acute hypoxic insult: a case report

Parkinson’s disease in a patient with GBA and LRRK2 covariants after acute hypoxic insult: a case report

Abstract Background The glucocerebrosidase (GBA) and leucine-rich repeat kinase 2 (LRRK2) genes are associated with the risk of sporadic Parkinson’s disease (PD). As an environmental factor, hypoxic insults may impair dopamine neurons in the substantia nigra and exacerbate PD symptoms. However, cova...

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Bibliographic Details
Main Authors: Yuting Tang, Lijian Wei, Zhuohua Wu, Pingyi Xu, Mingshu Mo
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Neurology
Subjects:
Parkinsonism
GBA
LRRK2
Hypoxic insult
Case report
Online Access:https://doi.org/10.1186/s12883-023-03269-5

Internet

https://doi.org/10.1186/s12883-023-03269-5

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