The 3q Oncogene <i>SEC62</i> Predicts Response to Neoadjuvant Chemotherapy and Regulates Tumor Cell Migration in Triple Negative Breast Cancer

The 3q Oncogene <i>SEC62</i> Predicts Response to Neoadjuvant Chemotherapy and Regulates Tumor Cell Migration in Triple Negative Breast Cancer

In the absence of targeted treatment options, neoadjuvant chemotherapy (NACT) is applied widely for triple-negative breast cancer (TNBC). Response to NACT is an important parameter predictive of oncological outcomes (progression-free and overall survival). An approach to the evaluation of predictive...

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Bibliographic Details
Main Authors: Julia C. Radosa, Mariz Kasoha, Merle Doerk, Annika Cullmann, Askin C. Kaya, Maximilian Linxweiler, Marc P. Radosa, Zoltan Takacs, Andrea Tirincsi, Sven Lang, Martin Jung, Julian Puppe, Barbara Linxweiler, Mathias Wagner, Rainer M. Bohle, Erich-Franz Solomayer, Julia S. M. Zimmermann
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
triple-negative breast cancer
neoadjuvant chemotherapy
oncogene <i>SEC62</i>
tumor pathogenesis
translational research
tumor cell migration
Online Access:https://www.mdpi.com/1422-0067/24/11/9576

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https://www.mdpi.com/1422-0067/24/11/9576

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