Metabolic Disruption Induced by mTOR Signaling Pathway Inhibition in Regulatory T-Cell Expansion for Clinical Application

Metabolic Disruption Induced by mTOR Signaling Pathway Inhibition in Regulatory T-Cell Expansion for Clinical Application

Background: Regulatory T cell (Treg) therapy is considered an alternative approach to induce tolerance in transplantation. If successful, this therapy may have implications on immunosuppression minimization/withdrawal to reduce drug-induced toxicity in patients. The aim of this study was to assess t...

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Bibliographic Details
Main Authors: Roberto Gedaly, Gabriel Orozco, Alexandre P. Ancheta, Mackenzie Donoho, Siddharth N. Desai, Fanny Chapelin, Aman Khurana, Lillie J. Lewis, Cuiping Zhang, Francesc Marti
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
regulatory T-cells
transplantation
cellular therapy
mTOR signaling
Online Access:https://www.mdpi.com/2073-4409/12/16/2066

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https://www.mdpi.com/2073-4409/12/16/2066

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