Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico

Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico

The identification and characterization of pharmacogenetic variants in Latin American populations is still an ongoing endeavor. Here, we investigated SNVs on genes listed by the Pharmacogenomics Knowledge Base in 1284 Mestizos and 94 Natives from Mexico. Five institutional cohorts with NGS data were...

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Bibliographic Details
Main Authors: Vanessa Gonzalez-Covarrubias, Marlet Morales-Franco, Omar F. Cruz-Correa, Angélica Martínez-Hernández, Humberto García-Ortíz, Francisco Barajas-Olmos, Alma Delia Genis-Mendoza, José Jaime Martínez-Magaña, Humberto Nicolini, Lorena Orozco, Xavier Soberón
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
Subjects:
pharmacogenomics
population variation
next generation sequencing
pharmacodynamics
pharmacokinetics
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01169/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.01169/full

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