Spontaneous locomotor activity and L-DOPA-induced dyskinesia are not linked in 6-OHDA parkinsonian rats

Spontaneous locomotor activity and L-DOPA-induced dyskinesia are not linked in 6-OHDA parkinsonian rats

Bradykinesia (slowness of movement) and other characteristic motor manifestations of Parkinson’s disease (PD) are alleviated by treatment with L-dihydroxyphenylalanine (L-DOPA). Long-term L-DOPA treatment, however, is associated with complications such as motor fluctuations and dyskinesia that sever...

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Bibliographic Details
Main Authors: Stefania eSgroi, Alain eKaelin-Lang, Christine eCapper-Loup
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Dyskinesia, Drug-Induced
Rotation
L-Dopa
Parkinson’s disease
Motor disorders
Spontaneous locomotor activity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00331/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00331/full

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