Cholesterol down-regulates BK channels stably expressed in HEK 293 cells.

Cholesterol is one of the major lipid components of the plasma membrane in mammalian cells and is involved in the regulation of a number of ion channels. The present study investigates how large conductance Ca(2+)-activated K(+) (BK) channels are regulated by membrane cholesterol in BK-HEK 293 cells...

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Bibliographic Details
Main Authors: Wei Wu, Yan Wang, Xiu-Ling Deng, Hai-Ying Sun, Gui-Rong Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3832390?pdf=render