Enhanced Differentiation Capacity and Transplantation Efficacy of Insulin-Producing Cell Clusters from Human iPSCs Using Permeable Nanofibrous Microwell-Arrayed Membrane for Diabetes Treatment

Enhanced Differentiation Capacity and Transplantation Efficacy of Insulin-Producing Cell Clusters from Human iPSCs Using Permeable Nanofibrous Microwell-Arrayed Membrane for Diabetes Treatment

Although pancreatic islet transplantation is a potentially curative treatment for insulin-dependent diabetes, a shortage of donor sources, low differentiation capacity, and transplantation efficacy are major hurdles to overcome before becoming a standard therapy. Stem cell-derived insulin-producing...

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Bibliographic Details
Main Authors: In Kyong Shim, Seong Jin Lee, Yu Na Lee, Dohui Kim, Hanse Goh, Jaeseung Youn, Jinah Jang, Dong Sung Kim, Song Cheol Kim
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceutics
Subjects:
iPSC
insulin-producing cells
diabetes
cell cluster
electrospinning
microwell
Online Access:https://www.mdpi.com/1999-4923/14/2/400

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https://www.mdpi.com/1999-4923/14/2/400

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