Genetics of <i>ABCB1</i> in Cancer

<i>ABCB1</i>, also known as <i>MDR1</i>, is a gene that encodes P-glycoprotein (P-gp), a membrane-associated ATP-dependent transporter. P-gp is widely expressed in many healthy tissues—in the gastrointestinal tract, liver, kidney, and at the blood–brain barrier. P-gp works to...

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Bibliographic Details
Main Authors: Katie T. Skinner, Antara M. Palkar, Andrew L. Hong
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/17/4236