Xerna™ TME Panel is a machine learning-based transcriptomic biomarker designed to predict therapeutic response in multiple cancers

Xerna™ TME Panel is a machine learning-based transcriptomic biomarker designed to predict therapeutic response in multiple cancers

IntroductionMost predictive biomarkers approved for clinical use measure single analytes such as genetic alteration or protein overexpression. We developed and validated a novel biomarker with the aim of achieving broad clinical utility. The Xerna™ TME Panel is a pan-tumor, RNA expression-based clas...

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Bibliographic Details
Main Authors: Mark Uhlik, Daniel Pointing, Seema Iyer, Luka Ausec, Miha Štajdohar, Robert Cvitkovič, Matjaž Žganec, Kerry Culm, Valerie Chamberlain Santos, Bronislaw Pytowski, Mokenge Malafa, Hong Liu, Arthur M. Krieg, Jeeyun Lee, Rafael Rosengarten, Laura Benjamin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
pan-tumor
immunotherapy
anti-angiogenic agent
diagnostic assay
predictive biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1158345/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1158345/full

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