Early Brain microRNA/mRNA Expression is Region-Specific After Neonatal Hypoxic-Ischemic Injury in a Mouse Model

Early Brain microRNA/mRNA Expression is Region-Specific After Neonatal Hypoxic-Ischemic Injury in a Mouse Model

Background: MicroRNAs (miRNAs) may be promising therapeutic targets for neonatal hypoxic-ischemic brain injury (HIBI) but targeting miRNA-based therapy will require more precise understanding of endogenous brain miRNA expression.Methods: Postnatal day 9 mouse pups underwent HIBI by unilateral caroti...

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Bibliographic Details
Main Authors: Eric S. Peeples, Namood-e Sahar, William Snyder, Karoly Mirnics
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Genetics
Subjects:
encephalopathy
cerebellum
next-generation sequencing
striatum
cortex
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.841043/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.841043/full

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