Astrocyte-Derived TGFβ1 Facilitates Blood–Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells

Astrocyte-Derived TGFβ1 Facilitates Blood–Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells

The blood–brain barrier is a specialized structure in mammals, separating the brain from the bloodstream and maintaining the homeostasis of the central nervous system. The barrier is composed of various types of cells, and the communication between these cells is critical to blood–brain barrier (BBB...

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Bibliographic Details
Main Authors: Jiyang Fu, Liang Li, Dong Huo, Shuli Zhi, Ruicheng Yang, Bo Yang, Bojie Xu, Tao Zhang, Menghong Dai, Chen Tan, Huanchun Chen, Xiangru Wang
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Brain Sciences
Subjects:
blood–brain barrier
TGFβ1
hedgehog signaling
Gli2
ZO-1
Online Access:https://www.mdpi.com/2076-3425/11/1/77

Internet

https://www.mdpi.com/2076-3425/11/1/77

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