Avocado Seeds-Mediated Alleviation of Cyclosporine A-Induced Hepatotoxicity Involves the Inhibition of Oxidative Stress and Proapoptotic Endoplasmic Reticulum Stress

Avocado Seeds-Mediated Alleviation of Cyclosporine A-Induced Hepatotoxicity Involves the Inhibition of Oxidative Stress and Proapoptotic Endoplasmic Reticulum Stress

Previous studies reported disrupted hepatic function and structure following the administration of cyclosporine A (CsA) in humans and animals. Recently, we found that avocado seeds (AvS) ameliorated CsA-induced nephrotoxicity in rats. As a continuation, herein we checked whether AvS could also atten...

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Bibliographic Details
Main Authors: Mohammed A. El-Magd, Amina M. G. Zedan, Nahla S. Zidan, Mohamed I. Sakran, Omar Bahattab, Atif Abdulwahab A. Oyouni, Osama M. Al-Amer, Adel I. Alalawy, Amira M. Elmoslemany
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
avocado seeds
cyclosporine A
hepatotoxicity
oxidative stress
ER stress
Online Access:https://www.mdpi.com/1420-3049/27/22/7859

Internet

https://www.mdpi.com/1420-3049/27/22/7859

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