Structural modeling of the N-terminal signal–receiving domain of IκBα

Structural modeling of the N-terminal signal–receiving domain of IκBα

The transcription factor nuclear factor-κB (NF-κB) exerts essential roles in many biological processes including cell growth, apoptosis and innate and adaptive immunity. The NF-kB inhibitor (IκBα) retains NF-κB in the cytoplasm and thus inhibits nuclear localization of NF-κB and its association with...

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Bibliographic Details
Main Authors: Samira eYazdi, SERDAR eDURDAGI, Michael eNaumann, Matthias eStein
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
Signal Transduction
NF-KappaB
Structural Homology, Protein
IkappaB
Secondary structure prediction
N-terminal extension
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00032/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00032/full

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