Modeling disordered protein interactions from biophysical principles.

Disordered protein-protein interactions (PPIs), those involving a folded protein and an intrinsically disordered protein (IDP), are prevalent in the cell, including important signaling and regulatory pathways. IDPs do not adopt a single dominant structure in isolation but often become ordered upon b...

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Bibliographic Details
Main Authors: Lenna X Peterson, Amitava Roy, Charles Christoffer, Genki Terashi, Daisuke Kihara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5402988?pdf=render