Sacituzumab govitecan and radiotherapy in metastatic, triple-negative, and BRCA-mutant breast cancer patient with active brain metastases: A case report

Sacituzumab govitecan and radiotherapy in metastatic, triple-negative, and BRCA-mutant breast cancer patient with active brain metastases: A case report

BackgroundTriple-negative breast cancer (TNBC) is an aggressive cancer subtype, owing to its high metastatic potential: Patients who develop brain metastases (BMs) have a poor prognosis due to the lack of effective systemic treatments. Surgery and radiation therapy are valid options, while pharmacot...

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Bibliographic Details
Main Authors: Pierluigi di Mauro, Greta Schivardi, Rebecca Pedersini, Lara Laini, Andrea Esposito, Vito Amoroso, Marta Laganà, Salvatore Grisanti, Deborah Cosentini, Alfredo Berruti
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
Subjects:
sacituzumab govitecan
triple-negative breast cancer
brain metastases
BRCA2
antibody-drug conjugate
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1139372/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1139372/full

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