Synthesis and in vitro antibacterial, antifungal, anti-proliferative activities of novel adamantane-containing thiazole compounds

Synthesis and in vitro antibacterial, antifungal, anti-proliferative activities of novel adamantane-containing thiazole compounds

Abstract A series of (Z)-N-(adamantan-1-yl)-3,4-diarylthiazol-2(3H)-imines (5a-r) was synthesized via condensation of 1-(adamantan-1-yl)-3-arylthioureas (3a-c) with various aryl bromomethyl ketones (4a-f). The structures of the synthesized compounds were characterized by 1H NMR, 13C NMR and by X-ray...

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Bibliographic Details
Main Authors: Eman T. Warda, Mahmoud B. El-Ashmawy, El-Sayed E. Habib, Mohammed S. M. Abdelbaky, Santiago Garcia-Granda, Subbiah Thamotharan, Ali A. El-Emam
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-25390-0

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https://doi.org/10.1038/s41598-022-25390-0

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