Astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors

Astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors

Abstract Background Little is known about how the obesogenic environment influences emotional states associated with glial responses and neuronal function. Here, we investigated glial reactivation and neuronal electrophysiological properties in emotion-related brain regions of high-fat diet (HFD) an...

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Bibliographic Details
Main Authors: Gang Yu, Feng Cao, Tingting Hou, Yunsheng Cheng, Benli Jia, Liang Yu, Wanjing Chen, Yanyan Xu, Mingming Chen, Yong Wang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Neuroinflammation
Subjects:
Obesity
High-fat diet
Ob/ob
Chronic social defeated stress
Astrocyte
Stress
Online Access:https://doi.org/10.1186/s12974-022-02529-4

Internet

https://doi.org/10.1186/s12974-022-02529-4

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