Water layer and radiation damage effects on the orientation recovery of proteins in single-particle imaging at an X-ray free-electron laser

Abstract The noise caused by sample heterogeneity (including sample solvent) has been identified as one of the determinant factors for a successful X-ray single-particle imaging experiment. It influences both the radiation damage process that occurs during illumination as well as the scattering patt...

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Bibliographic Details
Main Authors: Juncheng E, Michal Stransky, Zhou Shen, Zoltan Jurek, Carsten Fortmann-Grote, Richard Bean, Robin Santra, Beata Ziaja, Adrian P. Mancuso
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43298-1