Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial

Hormonal contraception may alter women’s susceptibility to HIV. Here, the authors report the results of a randomized clinical trial substudy assessing the effects of injectable Net-En, oral contraceptives (COC) and Nuvaring on vaginal microbiota and cytokines, associating COC with lower microbial di...

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Bibliographic Details
Main Authors: Christina Balle, Iyaloo N. Konstantinus, Shameem Z. Jaumdally, Enock Havyarimana, Katie Lennard, Rachel Esra, Shaun L. Barnabas, Anna-Ursula Happel, Zoe Moodie, Katherine Gill, Tanya Pidwell, Ulas Karaoz, Eoin Brodie, Venessa Maseko, Hoyam Gamieldien, Steven E. Bosinger, Landon Myer, Linda-Gail Bekker, Jo-Ann S. Passmore, Heather B. Jaspan
Format: Article
Language:English
Published: Nature Portfolio 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19382-9