Deregulation of circ_003912 contributes to pathogenesis of erosive oral lichen planus by via sponging microRNA-123, -647 and -31 and upregulating FOXP3

Deregulation of circ_003912 contributes to pathogenesis of erosive oral lichen planus by via sponging microRNA-123, -647 and -31 and upregulating FOXP3

Abstract Background The FOXP3/miR-146a/NF-κB axis was previously reported to modulate the induction and function of CD4+ Treg cells to alleviate oral lichen planus. Also, other signaling pathways including microRNA-155-IFN-γ loop and FOXP3/miR-146a/TRAF6 pathways were reported to be involved in the...

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Bibliographic Details
Main Authors: Zhen Huang, Fen Liu, Wenjuan Wang, Shaobo Ouyang, Ting Sang, Zikun Huang, Lan Liao, Jun Wu
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Molecular Medicine
Subjects:
Oral lichen planus
CD4+ Treg cells
FOXP3
miR-146a
circRNA
TRAF6
Online Access:https://doi.org/10.1186/s10020-021-00382-4

Internet

https://doi.org/10.1186/s10020-021-00382-4

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