The protocadherins, <it>PCDHB1 </it>and <it>PCDH7</it>, are regulated by MeCP2 in neuronal cells and brain tissues: implication for pathogenesis of Rett syndrome

The protocadherins, <it>PCDHB1 </it>and <it>PCDH7</it>, are regulated by MeCP2 in neuronal cells and brain tissues: implication for pathogenesis of Rett syndrome

<p>Abstract</p> <p>Background</p> <p>Rett syndrome is a neurodevelopmental and autistic disease caused by mutations of <it>Methyl-CpG-binding protein 2 </it>(<it>MECP2</it>) gene. MeCP2 protein is mainly expressed in neurons and binds to methylat...

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Main Authors: Nakagawa Takayuki, Kudo Shinichi, Takahashi Kenichiro, Endoh Kazushi, Goto Yu-ichi, Itoh Masayuki, Soutome Masaki, Hirasawa Takae, Miyake Kunio, Yokoi Sana, Taira Takahiro, Inazawa Johji, Kubota Takeo
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/12/81

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http://www.biomedcentral.com/1471-2202/12/81

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