Hypoxia-induced lncRNA MRVI1-AS1 accelerates hepatocellular carcinoma progression by recruiting RNA-binding protein CELF2 to stabilize SKA1 mRNA
Abstract Background Long non-coding RNAs (lncRNAs) perform a vital role during the progression of hepatocellular carcinoma (HCC). Here, we aimed to identify a novel lncRNA involved in HCC development and elucidate the underlying molecular mechanism. Methods The RT-qPCR and TCGA dataset analysis were...
Main Authors: | Hang Tuo, Runkun Liu, Yufeng Wang, Wei Yang, Qingguang Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
|
Series: | World Journal of Surgical Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12957-023-02993-z |
Similar Items
-
Circular RNA FAT atypical cadherin 1 (circFAT1)/microRNA-525-5p/spindle and kinetochore-associated complex subunit 1 (SKA1) axis regulates oxaliplatin resistance in breast cancer by activating the notch and Wnt signaling pathway
by: Ye Yao, et al.
Published: (2021-01-01) -
Hypoxia-induced SKA3 promoted cholangiocarcinoma progression and chemoresistance by enhancing fatty acid synthesis via the regulation of PAR-dependent HIF-1a deubiquitylation
by: Yananlan Chen, et al.
Published: (2023-10-01) -
METTL3-induced lncRNA GBAP1 promotes hepatocellular carcinoma progression by activating BMP/SMAD pathway
by: Runkun Liu, et al.
Published: (2023-09-01) -
Intracellular acidity impedes KCa3.1 activation by Riluzole and SKA-31
by: Marco Cozzolino, et al.
Published: (2024-04-01) -
Loss of PKGIβ/IRAG1 Signaling Causes Anemia-Associated Splenomegaly
by: Michael Majer, et al.
Published: (2021-05-01)