Genetic causality and site-specific relationship between sarcopenia and osteoarthritis: a bidirectional Mendelian randomization study

Genetic causality and site-specific relationship between sarcopenia and osteoarthritis: a bidirectional Mendelian randomization study

Background: Previous studies demonstrated a controversial relationship between sarcopenia (SP) and osteoarthritis (OA) and their genetic causality is unclear. Thus, we conducted a Mendelian randomization (MR) analysis to evaluate the possible causal association between sarcopenia-related traits (app...

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Bibliographic Details
Main Authors: Xue-Min Jia, Ting-Ting Deng, Hang Su, Hao-Jun Shi, Hao Qin, Gong-Chang Yu, Ying Yin, Fan-Jie Liu, Bin Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Genetics
Subjects:
sarcopenia
osteoarthritis
Mendelian randomization
degenerative musculoskeletal diseases
causal relationship
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1340245/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1340245/full

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