Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients

Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients

Abstract Background The objective of this study was to investigate cellular bioenergetics in primary skin fibroblasts derived from patients with amyotrophic lateral sclerosis (ALS) and to determine if they can be used as classifiers for patient stratification. Methods We assembled a collection of un...

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Bibliographic Details
Main Authors: Csaba Konrad, Hibiki Kawamata, Kirsten G. Bredvik, Andrea J. Arreguin, Steven A. Cajamarca, Jonathan C. Hupf, John M. Ravits, Timothy M. Miller, Nicholas J. Maragakis, Chadwick M. Hales, Jonathan D. Glass, Steven Gross, Hiroshi Mitsumoto, Giovanni Manfredi
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Molecular Neurodegeneration
Subjects:
Bioenergetics
Mitochondria
ALS
Fibroblasts
PLS
Machine learning
Online Access:http://link.springer.com/article/10.1186/s13024-017-0217-5

Internet

http://link.springer.com/article/10.1186/s13024-017-0217-5

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