Development of SimCells as a novel chassis for functional biosensors

Abstract This work serves as a proof-of-concept for bacterially derived SimCells (Simple Cells), which contain the cell machinery from bacteria and designed DNA (or potentially a simplified genome) to instruct the cell to carry out novel, specific tasks. SimCells represent a reprogrammable chassis w...

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Bibliographic Details
Main Authors: Cordelia P. N. Rampley, Paul A. Davison, Pu Qian, Gail M. Preston, C. Neil Hunter, Ian P. Thompson, Ling Juan Wu, Wei E. Huang
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07391-6