Decreased breadth of the antibody response to the spike protein of SARS-CoV-2 after repeated vaccination

IntroductionThe rapid development of vaccines to prevent COVID-19 has raised the need to compare the capacity of different vaccines in terms of developing a protective humoral response. Previous studies have shown inconsistent results in this area, highlighting the importance of further research to...

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Bibliographic Details
Main Authors: Lydia Horndler, Pilar Delgado, Salvador Romero-Pinedo, Marina Quesada, Ivaylo Balabanov, Rocío Laguna-Goya, Patricia Almendro-Vázquez, Miguel A. Llamas, Manuel Fresno, Estela Paz-Artal, Hisse M. van Santen, Stela Álvarez-Fernández, Asunción Olmo, Balbino Alarcón
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1157263/full