Generation of induced pluripotent stem cells (CSSi017-A)(12862) from an ALS patient carrying a repeat expansion in the C9orf72 gene

Generation of induced pluripotent stem cells (CSSi017-A)(12862) from an ALS patient carrying a repeat expansion in the C9orf72 gene

Genetic expansions of the hexanucleotide repeats (GGGGCC) in the C9orf72 gene appear in approximately 40% of patients with familial ALS and 7% of patients with sporadic ALS in the European population, making this mutation one of the most prevalent genetic mutations in ALS. Here, we generated a human...

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Bibliographic Details
Main Authors: G. Ruotolo, A. D'Anzi, A. Casamassa, M. Mazzoni, D. Ferrari, I. Lombardi, R.M. Carletti, C. D'Asdia, I. Torrente, K. Frezza, S. Lattante, M. Sabatelli, M. Pennuto, A.L. Vescovi, J. Rosati
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506124001107

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http://www.sciencedirect.com/science/article/pii/S1873506124001107

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