Next-Generation Sequencing Based HLA Typing: Deciphering Immunogenetic Aspects of Sarcoidosis

Next-Generation Sequencing Based HLA Typing: Deciphering Immunogenetic Aspects of Sarcoidosis

Unraveling of the HLA-related immunogenetic basis of several immune disorders is complex due to the extensive HLA polymorphism and strong linkage-disequilibrium between HLA loci. A lack of in phase sequence information, a relative deficiency of high resolution genotyping including non-coding regions...

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Bibliographic Details
Main Authors: Amit Kishore, Martin Petrek
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Genetics
Subjects:
HLA
next-generation sequencing
genotyping
immune diseases
disease association
sarcoidosis
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00503/full

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https://www.frontiersin.org/article/10.3389/fgene.2018.00503/full

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