Differential regulation of lineage-determining transcription factor expression in innate lymphoid cell and adaptive T helper cell subsets

Differential regulation of lineage-determining transcription factor expression in innate lymphoid cell and adaptive T helper cell subsets

CD4 T helper (Th) cell subsets, including Th1, Th2 and Th17 cells, and their innate counterparts innate lymphoid cell (ILC) subsets consisting of ILC1s, ILC2s and ILC3s, display similar effector cytokine-producing capabilities during pro-inflammatory immune responses. These lymphoid cell subsets uti...

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Bibliographic Details
Main Authors: Difeng Fang, Ayanna Healy, Jinfang Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
lineage-determining transcription factor
epigenetic modification
CD4 T helper cells
innate lymphoid cells
Th cell differentiation
ILC development
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1081153/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1081153/full

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