Bayesian Calibration of Electrophysiology Models Using Restitution Curve Emulators

Bayesian Calibration of Electrophysiology Models Using Restitution Curve Emulators

Calibration of cardiac electrophysiology models is a fundamental aspect of model personalization for predicting the outcomes of cardiac therapies, simulation testing of device performance for a range of phenotypes, and for fundamental research into cardiac function. Restitution curves provide inform...

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Bibliographic Details
Main Authors: Sam Coveney, Cesare Corrado, Jeremy E. Oakley, Richard D. Wilkinson, Steven A. Niederer, Richard H. Clayton
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
restitution
electrophysiology
cardiology
Gaussian processes
emulation
sensitivity analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.693015/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.693015/full

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